RS641738 Unknown gene
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What This Variant Does
"The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Phosphatidylinositol (18:0_20:4) levels | T | OR: 0.36 | 9E-60 | PubMed |
| 1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) levels | C | OR: 0.29 | 2E-54 | PubMed |
| Phosphatidylinositol (16:0_18:2) levels | T | OR: 0.24 | 4E-45 | PubMed |
| Phosphatidylinositol (18:0_20:4) levels | T | OR: 0.29 | 2E-40 | PubMed |
| Phosphatidylinositol (18:0_18:1) levels | T | OR: 0.22 | 8E-40 | PubMed |
| 1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) levels | T | OR: 0.19 | 6E-37 | PubMed |
| Metabolite levels (1-linoleoylglycerophosphoinositol; 1-linoleoyl-GPI (18:2)) | C | OR: 0.2 | 1E-33 | PubMed |
| Lysophosphatidylinositol (20:4) [sn1] levels | T | OR: 0.24 | 3E-27 | PubMed |
| 1-linoleoyl-GPI (18:2) levels | T | OR: 0.16 | 2E-26 | PubMed |
| Platelet crit (UKB data field 30090) | T | β: 0.019 | 2E-26 | PubMed |
| Lysophosphatidylinositol (20:4) [sn2] levels | T | OR: 0.23 | 2E-26 | PubMed |
| Plasma 1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) levels in chronic kidney disease | T | OR: 0.17 | 2E-24 | PubMed |
| Platelet count | T | β: 0.019 | 3E-23 | PubMed |
| Platelet count | T | — | 7E-22 | PubMed |
| Phosphatidylinositol (18:0_20:3) (a) levels | T | OR: 0.2 | 4E-19 | PubMed |
| Platelet count (UKB data field 30080) | T | β: 0.015 | 1E-18 | PubMed |
| Platelet count | T | β: 0.017 | 1E-17 | PubMed |
| Phosphatidylinositol (18:0_20:3) (a) levels | T | OR: 0.18 | 3E-16 | PubMed |
| Metabolite levels (1-stearoyl-2-oleoyl-GPI (18:0/18:1)) | C | OR: 0.16 | 9E-16 | PubMed |
| Average diameter for LDL particles | T | β: 0.02 | 1E-14 | PubMed |