RS62048402 Unknown gene
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What This Variant Does
"Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Weight (minimum, inv-normal transformed) | G | OR: 0.12 | 6E-241 | PubMed |
| Blood urea nitrogen (BUN, mean, inv-norm transformed) | G | β: 0.048 | 5E-90 | PubMed |
| Weight | A | β: 0.071 | 4E-75 | PubMed |
| Edema (PheCode 782.3) | G | β: 0.09 | 1E-53 | PubMed |
| Obstructive sleep apnea | — | OR: 1.08 | 6E-52 | PubMed |
| Blood urea nitrogen (BUN, maximum, inv-norm transformed) | G | β: 0.038 | 2E-49 | PubMed |
| Hypertension (PheCode 401) | G | β: 0.085 | 2E-42 | PubMed |
| Polyneuropathy in diabetes (PheCode 250.6) | G | OR: 0.13 | 4E-38 | PubMed |
| Chronic venous insufficiency [CVI] (PheCode 456) | G | OR: 0.12 | 7E-38 | PubMed |
| Drinks per week | A | β: 0.011 | 1E-37 | PubMed |
| Chronic ulcer of leg or foot (PheCode 707.2) | G | OR: 0.13 | 1E-33 | PubMed |
| Chronic ulcer of skin (PheCode 707) | G | OR: 0.11 | 5E-33 | PubMed |
| Weight (mean, inv-normal transformed) | G | β: 0.087 | 3E-30 | PubMed |
| Cellulitis and abscess of leg, except foot (PheCode 681.5) | G | OR: 0.11 | 3E-25 | PubMed |
| Congestive heart failure; nonhypertensive (PheCode 428) | G | β: 0.07 | 4E-24 | PubMed |
| Breast cancer | A | β: 0.062 | 4E-23 | PubMed |
| Overweight, obesity and other hyperalimentation (PheCode 278) | G | OR: 0.14 | 2E-22 | PubMed |
| Medication use (diuretics) | A | β: 0.065 | 3E-21 | PubMed |
| hemoglobin (mean, inv-norm transformed) | G | β: 0.024 | 2E-20 | PubMed |
| Atrial fibrillation (MTAG) | A | OR: 9.2 | 3E-20 | PubMed |