RS6066825 Unknown gene
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What This Variant Does
"Strongly enhanced colorectal cancer risk stratification by combining family history and genetic risk..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Colorectal cancer | G | β: 0.081 | 2E-32 | PubMed |
| Colorectal cancer | A | β: 0.074 | 3E-18 | PubMed |
| Colorectal cancer | A | OR: 1.1 | 4E-17 | PubMed |
| Colorectal cancer or advanced adenoma | A | OR: 1.07 | 6E-15 | PubMed |
| Colorectal cancer | G | β: 0.094 | 3E-13 | PubMed |
| Colorectal cancer | — | OR: 0.91 | 8E-13 | PubMed |
| Colorectal cancer | A | OR: 1.1 | 8E-12 | PubMed |
| Colorectal cancer | A | OR: 1.1 | 4E-11 | PubMed |
| Early onset colorectal cancer | G | OR: 0.87 | 7E-11 | PubMed |
| Colon polyp | G | β: 0.061 | 4E-10 | PubMed |
| Red blood cell count | A | β: 0.008 | 2E-9 | PubMed |
| Colorectal cancer | A | OR: 1.09 | 4E-9 | PubMed |
| Colorectal cancer | G | OR: 0.13 | 5E-9 | PubMed |
| Otosclerosis | G | OR: 1.16 | 1E-8 | PubMed |
| Colorectal polyp (UKB data field 20002_1460) | — | OR: 0.94 | 3E-8 | PubMed |
| Colorectal cancer | G | OR: 0.91 | 3E-8 | PubMed |
| Cancer (pleiotropy) | A | OR: 1.12 | 6E-8 | PubMed |
| Colon cancer | A | OR: 1.14 | 1E-7 | PubMed |
| Colorectal cancer | A | OR: 1.06 | 2E-6 | PubMed |
| Colorectal cancer | G | OR: 0.91 | 6E-6 | PubMed |