RS600626 Unknown gene
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What This Variant Does
"[GWAS:Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)]"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Phospholipids in HDL | G | β: 0.06 | 2E-116 | PubMed |
| Free cholesterol in medium HDL | G | β: 0.06 | 5E-112 | PubMed |
| Total Lipids in HDL | G | β: 0.05 | 3E-95 | PubMed |
| Total concentration of lipoprotein particles | G | β: 0.05 | 4E-89 | PubMed |
| Phosphoglycerides levels | G | β: 0.04 | 1E-65 | PubMed |
| HDL cholesterol levels | G | β: 0.04 | 4E-65 | PubMed |
| High density lipoprotein cholesterol levels | — | — | 5E-64 | PubMed |
| Phosphatidylcholine levels | G | β: 0.04 | 1E-54 | PubMed |
| Total cholines levels | G | β: 0.04 | 5E-51 | PubMed |
| Ratio of omega-3 fatty acids to total fatty acids | A | β: 0.062 | 3E-30 | PubMed |
| 3-Hydroxybutyrate levels | G | β: 0.03 | 1E-24 | PubMed |
| Estimated degree of unsaturation | A | β: 0.053 | 5E-23 | PubMed |
| Degree of unsaturation (UKB data field 23443) | G | β: 0.06 | 5E-22 | PubMed |
| Degree of unsaturation | G | — | 1E-19 | PubMed |
| Ratio of 22:6 docosahexaenoic acid to total fatty acids | A | β: 0.046 | 2E-19 | PubMed |
| Cholesteryl Esters in IDL | G | β: 0.02 | 2E-16 | PubMed |
| total cholesterol (mean, inv-norm transformed) | A | β: 0.023 | 1E-13 | PubMed |
| Concentration of large HDL particles | A | β: 0.036 | 8E-12 | PubMed |
| Metabolite peak levels (QI6701) | G | OR: 0.2 | 1E-11 | PubMed |
| Total lipids in large HDL | A | β: 0.035 | 2E-11 | PubMed |