RS577721086 Unknown gene
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What This Variant Does
"Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Waist-to-hip ratio adjusted for BMI | — | — | 4E-286 | PubMed |
| Waist-hip ratio | — | — | 1E-274 | PubMed |
| Waist-to-hip ratio adjusted for BMI | T | OR: 0.17 | 7E-274 | PubMed |
| Waist-hip ratio | T | OR: 0.13 | 1E-170 | PubMed |
| Hip circumference adjusted for BMI | C | OR: 0.11 | 5E-67 | PubMed |
| Triglyceride levels | — | — | 9E-58 | PubMed |
| Triglycerides to Total Lipids in Small HDL percentage | C | β: 0.099 | 4E-57 | PubMed |
| Triglycerides in small HDL | C | β: 0.097 | 7E-55 | PubMed |
| Triglyceride to phosphoglyceride ratio | C | β: 0.098 | 8E-55 | PubMed |
| Triglycerides to Total Lipids in Medium HDL percentage | C | β: 0.094 | 2E-51 | PubMed |
| Cholesterol to Total Lipids in Medium HDL percentage | C | β: 0.092 | 3E-49 | PubMed |
| Triglycerides in small VLDL | C | β: 0.093 | 4E-49 | PubMed |
| R-spondin-3 levels | T | OR: 0.43 | 2E-47 | PubMed |
| Triglyceride levels (UKB data field 30870) | C | β: 0.056 | 4E-46 | PubMed |
| Triglycerides in very large VLDL | C | β: 0.091 | 2E-45 | PubMed |
| Waist-hip index | C | OR: 0.1 | 1E-44 | PubMed |
| Concentration of very large VLDL particles | C | β: 0.09 | 2E-44 | PubMed |
| Phospholipids in large VLDL | C | β: 0.09 | 4E-44 | PubMed |
| Triglyceride levels | T | β: 0.081 | 5E-44 | PubMed |
| Free Cholesterol to Total Lipids in Large LDL percentage | C | β: 0.06 | 9E-44 | PubMed |