RS55781567 Unknown gene
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What This Variant Does
"In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Lung cancer or family history of lung cancer | G | OR: 1.24 | 5E-115 | PubMed |
| Lung cancer | — | OR: 0.19 | 6E-106 | PubMed |
| Lung cancer | G | OR: 1.3 | 3E-103 | PubMed |
| Lung cancer in ever smokers | G | OR: 1.33 | 2E-78 | PubMed |
| Squamous cell lung carcinoma (conditioned on cigarettes per day) | C | OR: 0.77 | 2E-74 | PubMed |
| Cancer of bronchus; lung (PheCode 165.1) | C | OR: 0.22 | 7E-64 | PubMed |
| Cancer within the respiratory system (PheCode 165) | C | OR: 0.21 | 2E-61 | PubMed |
| Lung adenocarcinoma | — | OR: 0.19 | 2E-50 | PubMed |
| Lung adenocarcinoma | G | OR: 1.28 | 3E-48 | PubMed |
| Non-small cell lung cancer | G | OR: 1.27 | 8E-44 | PubMed |
| Non-small cell lung cancer | G | OR: 0.79 | 8E-44 | PubMed |
| Squamous cell lung carcinoma | — | OR: 0.21 | 2E-33 | PubMed |
| Aerodigestive squamous cell cancer (pleiotropy) | G | OR: 1.19 | 2E-29 | PubMed |
| Biological Father: Chronic Lung Disease including COPD, Emphysema or Bronchitis | C | OR: 0.1 | 5E-28 | PubMed |
| Lung adenocarcinoma | G | OR: 0.8 | 9E-26 | PubMed |
| Squamous cell lung carcinoma | G | OR: 0.78 | 2E-23 | PubMed |
| Dependence on respirator [Ventilator] or supplemental oxygen (PheCode 509.8) | C | OR: 0.14 | 1E-22 | PubMed |
| Solitary pulmonary nodule (PheCode 514.2) | C | β: 0.087 | 3E-21 | PubMed |
| What is your weight? (pounds, inv-normal transformed) | C | β: 0.028 | 2E-17 | PubMed |
| Biological Sibling: Chronic Lung Disease including COPD, Emphysema or Bronchitis | C | β: 0.096 | 2E-15 | PubMed |