RS5442 Unknown gene
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What This Variant Does
"Genetic Variants, Endothelial Function, and Risk of Preeclampsia Among American Indians"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Refractive error | — | — | 3E-62 | PubMed |
| Spherical equivalent | G | OR: 0.29 | 8E-40 | PubMed |
| Retinal thickness (pixel 88_54) | A | OR: 0.58 | 3E-29 | PubMed |
| Macular thickness | — | OR: 1.37 | 6E-26 | PubMed |
| Retinal vascular fractal density | A | OR: 0.13 | 1E-21 | PubMed |
| Myopia | A | OR: 0.19 | 6E-19 | PubMed |
| Retinal arteriolar width | G | OR: 0.75 | 2E-17 | PubMed |
| Refractive error | A | β: 0.097 | 4E-16 | PubMed |
| Spherical equivalent or myopia (age of diagnosis) | A | OR: 7.82 | 5E-15 | PubMed |
| Myopia | — | OR: 1.12 | 2E-14 | PubMed |
| Eye autorefraction and astigmatism (confirmatory factor analysis Factor 24) | — | — | 5E-14 | PubMed |
| Primary open angle glaucoma (MTAG) | A | OR: 0.13 | 5E-14 | PubMed |
| Primary open angle glaucoma (multi-trait analysis) | A | OR: 0.13 | 5E-14 | PubMed |
| Retinal nerve fibre layer thickness or ganglion cell inner plexiform layer thickness (MTAG) | A | OR: 0.69 | 2E-13 | PubMed |
| Ganglion cell inner plexiform layer (GCIPL) thickness | A | OR: 0.69 | 2E-13 | PubMed |
| Myopia (age of diagnosis) | A | β: 0.098 | 9E-13 | PubMed |
| Hypermetropia (PheCode 367.8) | G | β: 0.079 | 3E-12 | PubMed |
| Myopia (PheCode 367.1) | G | β: 0.076 | 8E-12 | PubMed |
| Hypermetropia (PheCode 367.8) | G | β: 0.085 | 2E-11 | PubMed |
| Open-angle glaucoma (PheCode 365.1) | G | β: 0.076 | 4E-11 | PubMed |