RS5219 Unknown gene
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What This Variant Does
"rs5219, also known as E23K, is a SNP in the KCNJ11 gene. The association between type-1 diabetes and...
Related Biomarkers
Glucose (Fasting)
monitor
moderate
GWAS Studies (19)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) | T | β: 0.045 | 8E-53 | PubMed |
| Type 2 diabetes | C | β: 0.069 | 3E-48 | PubMed |
| Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) | T | β: 0.038 | 1E-27 | PubMed |
| Type 2 diabetes (adjusted for BMI) | T | OR: 1.07 | 2E-22 | PubMed |
| Type 2 diabetes | T | OR: 1.06 | 6E-22 | PubMed |
| Glucose (fasting status unknown, mean, inv-norm transformed) | T | β: 0.03 | 1E-21 | PubMed |
| hematocrit (maximum, inv-norm transformed) | T | β: 0.02 | 2E-14 | PubMed |
| Glucose levels (UKB data field 30740) | C | β: 0.017 | 3E-14 | PubMed |
| hemoglobin (maximum, inv-norm transformed) | T | β: 0.018 | 1E-12 | PubMed |
| Systolic blood pressure | T | OR: 0.32 | 5E-12 | PubMed |
| Type 2 diabetes | T | OR: 1.14 | 7E-11 | PubMed |
| Type 2 diabetes | T | OR: 1.14 | 7E-11 | PubMed |
| Body mass index | C | β: 0.012 | 4E-10 | PubMed |
| Vertex-wise cortical surface area | T | OR: 5.95 | 3E-9 | PubMed |
| Mean arterial pressure | T | OR: 0.29 | 4E-9 | PubMed |
| Coronary artery disease (MTAG) | T | OR: 5.69 | 1E-8 | PubMed |
| Pulse pressure | T | OR: 0.18 | 3E-7 | PubMed |
| Type 2 diabetes | — | OR: 1.19 | 5E-7 | PubMed |
| Type 2 diabetes | T | OR: 1.04 | 4E-6 | PubMed |