RS4986970 Unknown gene
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What This Variant Does
"LCAT, HDL Cholesterol and Ischemic Cardiovascular Disease: A Mendelian Randomization Study of HDL Cholesterol in 54,500 Individuals"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Phospholipids to Total Lipids in Large LDL percentage | T | OR: 0.11 | 4E-83 | PubMed |
| Cholesteryl Esters in HDL | T | β: 0.09 | 3E-77 | PubMed |
| HDL cholesterol levels | T | β: 0.09 | 7E-77 | PubMed |
| Free Cholesterol to Total Lipids in Medium HDL percentage | T | β: 0.09 | 2E-73 | PubMed |
| Cholesteryl Esters in Large HDL | T | β: 0.08 | 4E-69 | PubMed |
| Concentration of large HDL particles | T | β: 0.08 | 7E-69 | PubMed |
| Cholesteryl Esters to Total Lipids in Large LDL percentage | T | β: 0.1 | 2E-68 | PubMed |
| Cholesterol in Large HDL | T | β: 0.08 | 1E-66 | PubMed |
| LCAT protein levels | T | OR: 0.26 | 3E-66 | PubMed |
| Free Cholesterol in HDL | T | β: 0.08 | 1E-65 | PubMed |
| Total lipids in large HDL | T | β: 0.08 | 8E-62 | PubMed |
| Total Lipids in HDL | T | β: 0.08 | 2E-59 | PubMed |
| Free Cholesterol to Total Lipids in Very Large HDL percentage | T | β: 0.08 | 4E-59 | PubMed |
| Phospholipids in large HDL | T | β: 0.08 | 5E-57 | PubMed |
| Cholesterol in Medium HDL | T | β: 0.08 | 8E-57 | PubMed |
| Free cholesterol in medium HDL | T | β: 0.08 | 8E-57 | PubMed |
| Concentration of HDL particles | T | β: 0.08 | 3E-56 | PubMed |
| Apolipoprotein A1 levels | T | β: 0.08 | 3E-56 | PubMed |
| Cholesteryl Esters in Medium HDL | T | β: 0.08 | 1E-55 | PubMed |
| Free cholesterol in large HDL | T | β: 0.07 | 5E-55 | PubMed |