RS493258 Unknown gene
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What This Variant Does
"Evaluation of new and established age-related macular degeneration susceptibility genes in the Women..."
GWAS Studies (19)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Phosphatidylcholine_33:4_[M+H]1+/Phosphatidylethanolamine_36:4_[M+H]1+/Phosphatidate_38:5_[M+NH4]1+ levels | T | OR: 0.22 | 1E-74 | PubMed |
| Phosphatidylethanolamine_38:6_[M-H]1- levels | T | OR: 0.2 | 3E-68 | PubMed |
| Phosphatidylcholine_35:4_[M+H]1+/Phosphatidylethanolamine_38:4_[M+H]1+/Phosphatidate_40:5_[M+NH4]1+ levels | T | OR: 0.2 | 2E-65 | PubMed |
| Phosphatidylcholine_35:6_[M+H]1+/Phosphatidylethanolamine_38:6_[M+H]1+/Phosphatidate_40:7_[M+NH4]1+ levels | T | OR: 0.2 | 6E-63 | PubMed |
| Phosphatidylethanolamine_36:4_[M-H]1- levels | T | OR: 0.18 | 7E-57 | PubMed |
| Phosphatidylcholine_31:2_[M+H]1+/Phosphatidylethanolamine_34:2_[M+H]1+/Phosphatidate_36:3_[M+NH4]1+ levels | T | OR: 0.18 | 6E-50 | PubMed |
| Phosphatidylethanolamine_34:2_[M-H]1- levels | T | OR: 0.13 | 3E-31 | PubMed |
| Phosphatidylcholine_37:6_[M+H]1+/Phosphatidylethanolamine_40:6_[M+H]1+/Phosphatidate_42:7_[M+NH4]1+ levels | T | OR: 0.15 | 8E-26 | PubMed |
| Serum metabolite levels (CMS) | — | β: 0.067 | 2E-22 | PubMed |
| Phosphatidylethanolamine_38:5_[M-H]1- levels | T | β: 0.091 | 6E-20 | PubMed |
| Diacylglycerol_38:6_[M+H-H2O]1+ levels | T | β: 0.077 | 1E-14 | PubMed |
| Phosphatidylethanolamine_36:3_[M-H]1- levels | T | β: 0.075 | 5E-13 | PubMed |
| Lysophosphatidylethanolamine_16:0_[M-H]1- levels | T | β: 0.076 | 1E-12 | PubMed |
| Phosphatidylethanolamine(36:4)_[M-H]1- levels | C | β: 0.062 | 2E-11 | PubMed |
| Phosphatidylethanolamine(36:4)_[M+H]1+ levels | G | β: 0.083 | 2E-11 | PubMed |
| Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels | C | β: 0.036 | 2E-11 | PubMed |
| Phosphatidylethanolamine_34:1_[M-H]1- levels | T | β: 0.067 | 5E-11 | PubMed |
| Age-related macular degeneration | C | OR: 1.16 | 2E-8 | PubMed |
| Serum metabolite levels | — | β: 0.074 | 7E-7 | PubMed |