RS4702 Unknown gene
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What This Variant Does
"A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Vertex-wise sulcal depth | G | OR: 18.31 | 7E-75 | PubMed |
| Height | G | β: 0.01 | 9E-57 | PubMed |
| Insomnia | A | β: 0.011 | 3E-31 | PubMed |
| Schizophrenia | — | — | 6E-26 | PubMed |
| Schizophrenia | G | OR: 1.08 | 6E-25 | PubMed |
| Externalizing behaviour (multivariate analysis) | G | β: 0.012 | 1E-23 | PubMed |
| Schizophrenia or ER positive breast cancer (pleiotropy) | G | — | 1E-22 | PubMed |
| Schizophrenia or breast cancer (pleiotropy) | G | — | 2E-22 | PubMed |
| GDF2 protein levels | A | β: 0.044 | 7E-21 | PubMed |
| Major depressive disorder | — | β: 0.024 | 3E-19 | PubMed |
| Vertex-wise cortical thickness | G | OR: 8.89 | 6E-19 | PubMed |
| Cortical thickness | G | — | 1E-17 | PubMed |
| Insomnia | A | β: 0.01 | 3E-17 | PubMed |
| HRC protein levels | A | β: 0.048 | 3E-17 | PubMed |
| Number of sexual partners | A | β: 0.02 | 6E-17 | PubMed |
| Whole brain restricted directional diffusion (multivariate analysis) | — | — | 7E-17 | PubMed |
| Age at first sexual intercourse | G | β: 0.017 | 1E-16 | PubMed |
| Insomnia | G | OR: 1.05 | 7E-16 | PubMed |
| BMP10 protein levels | A | β: 0.041 | 1E-15 | PubMed |
| Schizophrenia | — | OR: 1.08 | 2E-15 | PubMed |