RS4680 Unknown gene

Other Chr 22:19963748
Upload your DNA to see your genotype for this variant.
What This Variant Does
"rs4680 (Val158Met) is a well studied SNP in the COMT gene. The COMT gene codes for the COMT enzyme, ...
GWAS Studies (20)
Trait Risk Allele OR / Beta P-value Study
COMT/HNRNPK protein level ratio OR: 0.76 4E-3035 PubMed
CA13/COMT protein level ratio OR: 0.68 5E-2335 PubMed
COMT/ITGB1BP2 protein level ratio OR: 0.64 1E-2112 PubMed
ABHD14B/COMT protein level ratio OR: 0.65 7E-2054 PubMed
COMT/RHOC protein level ratio OR: 0.61 4E-1820 PubMed
X-11593 levels A OR: 0.54 3E-613 PubMed
2-o-methylascorbic acid levels A OR: 0.44 7E-226 PubMed
2-o-methylascorbic acid levels A OR: 0.52 2E-185 PubMed
X-11593--O-methylascorbate levels A β: 0.049 5E-178 PubMed
Plasma 2-O-methylascorbic acid levels in chronic kidney disease A OR: 0.24 5E-174 PubMed
Urine 2-O-methylascorbic acid levels in chronic kidney disease A OR: 0.22 4E-161 PubMed
X-12707 levels A OR: 0.24 4E-120 PubMed
Urine X-12708 levels in chronic kidney disease A OR: 0.21 2E-60 PubMed
Urinary metabolite modules (eigenmetabolites) in chronic kidney disease G β: 0.012 5E-54 PubMed
Serum metabolite levels β: 0.049 1E-48 PubMed
Metabolite peak levels (QI2727) A OR: 0.41 6E-39 PubMed
X-12707 levels A OR: 0.23 3E-32 PubMed
Glucuronide of piperine metabolite c17h21no3 (4) (X-01911) levels G OR: 0.18 1E-29 PubMed
Urinary metabolite levels in chronic kidney disease G OR: 0.23 2E-28 PubMed
Urine glucuronide of piperine metabolite C17H21NO3 (5)* levels in chronic kidney disease A OR: 0.27 1E-25 PubMed
Ask Dr. Hemsworth about this variant