RS459193 Unknown gene
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What This Variant Does
"Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Waist-to-hip ratio adjusted for BMI | A | β: 0.029 | 3E-49 | PubMed |
| Glucose (fasting status unknown, mean, inv-norm transformed) | A | β: 0.041 | 3E-44 | PubMed |
| Glucose (fasting status unknown, maximum, inv-norm transformed) | A | β: 0.038 | 1E-39 | PubMed |
| Diabetes mellitus (PheCode 250) | A | β: 0.068 | 2E-37 | PubMed |
| Type 2 diabetes (PheCode 250.2) | A | β: 0.068 | 5E-37 | PubMed |
| Glucose (fasting status unknown, maximum, inv-norm transformed) | A | β: 0.036 | 9E-37 | PubMed |
| Albumin levels | A | β: 0.021 | 1E-36 | PubMed |
| Diabetes / "Sugar" | A | β: 0.074 | 2E-34 | PubMed |
| Metabolic syndrome | — | β: 0.027 | 4E-33 | PubMed |
| high density lipoprotein cholesterol (HDLC, mean, inv-norm transformed) | A | β: 0.038 | 3E-32 | PubMed |
| high density lipoprotein cholesterol (HDLC, maximum, inv-norm transformed) | A | β: 0.036 | 3E-30 | PubMed |
| Type 2 diabetes | G | β: 0.1 | 6E-30 | PubMed |
| Triglycerides | A | β: 0.032 | 9E-29 | PubMed |
| Linoleic acid to total fatty acids percentage | G | β: 0.02 | 1E-27 | PubMed |
| Waist-hip ratio and HDL-C (pairwise) | A | — | 4E-25 | PubMed |
| Diabetic retinopathy (PheCode 250.7) | A | β: 0.087 | 7E-25 | PubMed |
| Hemoglobin A1c (HbA1c, maximum, inv-norm transformed) | A | β: 0.033 | 2E-24 | PubMed |
| triglyceride (minimum, inv-norm transformed) | A | β: 0.029 | 6E-24 | PubMed |
| HDL cholesterol | A | β: 0.029 | 2E-23 | PubMed |
| Hemoglobin A1c (HbA1c, mean, inv-norm transformed) | A | β: 0.033 | 2E-23 | PubMed |