RS4409785 Unknown gene
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What This Variant Does
"One of 42 more SNPs associated with rheumatoid arthritis based on a meta-analysis of 30,000 patients..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Hypothyroidism | C | β: 0.085 | 5E-78 | PubMed |
| Hypothyroidism | C | β: 0.083 | 8E-68 | PubMed |
| Hypothyroidism | C | β: 0.099 | 2E-56 | PubMed |
| Medication use (thyroid preparations) | C | OR: 0.15 | 2E-35 | PubMed |
| Medication use (thyroid preparations) | C | OR: 0.14 | 2E-32 | PubMed |
| Hypothyroidism | C | OR: 0.15 | 4E-32 | PubMed |
| Hypothyroidism | T | OR: 0.12 | 2E-31 | PubMed |
| Hypothyroidism | — | — | 2E-31 | PubMed |
| Autoimmune thyroid disease | C | OR: 1.15 | 2E-31 | PubMed |
| Hypothyroidism | C | OR: 1.12 | 5E-27 | PubMed |
| Graves' disease | C | OR: 0.16 | 1E-26 | PubMed |
| Autoimmune thyroid disease | C | OR: 1.14 | 1E-24 | PubMed |
| Basal cell carcinoma (MTAG) | C | — | 7E-23 | PubMed |
| Hypothyroidism NOS (PheCode 244.4) | T | β: 0.071 | 8E-23 | PubMed |
| Hypothyroidism (PheCode 244) | T | β: 0.068 | 7E-22 | PubMed |
| Autoimmune traits | — | — | 4E-21 | PubMed |
| Graves' disease | C | OR: 0.15 | 8E-18 | PubMed |
| Hypothyroidism NOS (PheCode 244.4) | T | β: 0.075 | 1E-17 | PubMed |
| Hypothyroidism (PheCode 244) | T | β: 0.073 | 3E-17 | PubMed |
| Sex hormone-binding globulin levels | — | β: 0.033 | 5E-16 | PubMed |