RS4268748 Unknown gene
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What This Variant Does
"Susceptibility loci associated cutaneous squamous cell carcinoma invasiveness."
GWAS Studies (12)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Actinic keratosis | C | OR: 1.25 | 2E-61 | PubMed |
| Squamous cell carcinoma | C | OR: 1.33 | 2E-44 | PubMed |
| Diseases of sebaceous glands (PheCode 706) | T | β: 0.089 | 1E-39 | PubMed |
| Vitiligo | T | OR: 1.41 | 3E-33 | PubMed |
| Seborrheic keratosis (PheCode 702.2) | T | β: 0.068 | 3E-31 | PubMed |
| Seborrheic keratosis (PheCode 702.2) | T | β: 0.065 | 4E-22 | PubMed |
| Benign neoplasm of skin (PheCode 216) | T | β: 0.074 | 7E-19 | PubMed |
| Skin aging (microtopography measurement) | T | OR: 0.13 | 1E-15 | PubMed |
| Skin colour saturation | C | β: 0.009 | 3E-15 | PubMed |
| Melanoma in situ | T | OR: 0.19 | 1E-13 | PubMed |
| Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) | T | — | 7E-12 | PubMed |
| Actinic keratosis | C | OR: 1.29 | 2E-9 | PubMed |