RS4132601 IKZF1

Health Risk Chr 7:50402905 snv 3 prime UTR variant
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What This Variant Does
"23andMe blog Acute lymphoblastic leukemia *each rs4132601(G) 1.69x odds of ALL *each rs7089424(G) 1...."
Associated Conditions
Leukemia
acute lymphocytic
susceptibility to
2
Leukemia
acute lymphocytic
susceptibility to
2
GWAS Studies (3)
Trait Risk Allele OR / Beta P-value Study
Acute lymphoblastic leukemia in childhood (B cell precursor) — OR: 1.75 6E-55 PubMed
Acute lymphoblastic leukemia (childhood) C OR: 1.69 1E-19 PubMed
Acute lymphoblastic leukemia (childhood) G OR: 1.43 8E-13 PubMed
Population Frequencies
gnomAD ALL
23.2%
1kG AFR
17.5%
1kG ALL
22.1%
1kG AMR
23.3%
1kG EAS
10.8%
1kG EUR
68.2%
1kG SAS
29.3%
Other Variants in IKZF1
rs869312883 rs770551610 rs869312884 rs1064796324 rs1131690788 rs1554391793 rs778820674 rs1245618829 rs1435621658 rs11978267
Ask Dr. Hemsworth about this variant