RS3918290 DPYD
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What This Variant Does
"23andMe reports that the A allele of rs3918290 is associated with the rare recessive disorder dihydr...
Associated Conditions
Dihydropyrimidine dehydrogenase deficiency
Fluorouracil response
Hirschsprung disease
susceptibility to
1
fluorouracil response - Toxicity
fluorouracil response - Other
capecitabine response - Toxicity
tegafur response - Toxicity
Inborn genetic diseases
DPYD-related disorder
Sarcoma
Lymphoma
Malignant tumor of esophagus
Lung cancer
GWAS Studies (1)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Uracil levels | T | OR: 1.43 | 6E-148 | PubMed |
Other Variants in DPYD