RS3829241 TPCN2
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What This Variant Does
"This SNP influences appearance and is located in the TPCN2 gene. A study of 5130 Icelanders (with fu...
Associated Conditions
SKIN/HAIR/EYE PIGMENTATION
VARIATION IN
10
SKIN/HAIR/EYE PIGMENTATION
VARIATION IN
10
GWAS Studies (11)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Blond vs. brown/black hair color | A | OR: 1.27 | 5E-188 | PubMed |
| Sex hormone-binding globulin levels and heel estimated bone mineral density | — | — | 5E-77 | PubMed |
| Sex hormone-binding globulin levels adjusted for BMI and heel estimated bone mineral density | — | — | 5E-73 | PubMed |
| Heel bone mineral density | — | — | 3E-63 | PubMed |
| Heel bone mineral density | G | β: 0.031 | 8E-62 | PubMed |
| Heel bone mineral density | — | β: 0.03 | 9E-51 | PubMed |
| CTSS protein levels | A | β: 0.041 | 2E-18 | PubMed |
| Height | A | β: 0.022 | 4E-14 | PubMed |
| Heel bone mineral density | G | β: 0.032 | 6E-13 | PubMed |
| Bone density (confirmatory factor analysis Factor 19) | — | — | 1E-12 | PubMed |
| Hip circumference adjusted for BMI | A | β: 0.018 | 1E-8 | PubMed |
Other Variants in TPCN2