Genetic variant
rs3791679
rs3791679 is a single-letter difference in human DNA, on chromosome 2. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs3791679 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs3791679, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs3791679
- Position
- chr2:55869757
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| What is your height? (cm, inv-normal transformed) | A | OR 0.14 | 1E-323 | PubMed |
| Height | G | β 0.071 | 1E-300 | PubMed |
| Height | G | β 0.071 | 1E-300 | PubMed |
| Height | G | β 0.047 | 4E-215 | PubMed |
| EFEMP1 protein levels | G | OR 0.18 | 4E-201 | PubMed |
| Height | G | β 0.071 | 1E-168 | PubMed |
| height (mean, inv-normal transformed) | A | OR 0.12 | 4E-165 | PubMed |
| Height (maximum, inv-normal transformed) | A | OR 0.12 | 4E-162 | PubMed |
| height (minimum, inv-normal transformed) | A | OR 0.11 | 1E-153 | PubMed |
| Height | G | β 0.07 | 2E-139 | PubMed |
| What is your height? (cm, inv-normal transformed) | A | OR 0.11 | 2E-110 | PubMed |
| Inguinal hernia | G | OR 0.82 | 3E-87 | PubMed |
| Height | A | β 0.056 | 9E-87 | PubMed |
| Height | — | β 0.063 | 4E-82 | PubMed |
| Abdominal hernia (PheCode 550) | A | OR 0.13 | 3E-81 | PubMed |
| Abdominal hernia (PheCode 550) | A | OR 0.13 | 1E-73 | PubMed |
| Inguinal hernia | G | OR 0.82 | 3E-72 | PubMed |
| Height | A | β 0.06 | 2E-67 | PubMed |
| EGF-containing fibulin-like extracellular matrix protein 1 levels | A | OR 0.26 | 6E-67 | PubMed |
| Height | G | β 0.038 | 2E-61 | PubMed |
Sources
- dbSNP: rs3791679 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies