RS3775291 Unknown gene
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What This Variant Does
"rs3775291 is a SNP in the TLR3 gene associated with an amino acid change in the corresponding protei...
GWAS Studies (17)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Toll-like receptor 3 levels | T | OR: 0.81 | 7E-842 | PubMed |
| Toll-like receptor 3 levels | T | OR: 0.72 | 2E-131 | PubMed |
| TLR3 protein levels | T | OR: 1.09 | 1E-83 | PubMed |
| Hypothyroidism | T | β: 0.058 | 8E-51 | PubMed |
| Hypothyroidism | T | β: 0.06 | 2E-48 | PubMed |
| Toll-like receptor 3 level in Chronic kidney disease with hypertension and no diabetes (16918_198) | T | OR: 1.1 | 1E-19 | PubMed |
| Medication use (thyroid preparations) | T | β: 0.087 | 3E-18 | PubMed |
| Hypothyroidism NOS (PheCode 244.4) | C | β: 0.053 | 4E-17 | PubMed |
| Hypothyroidism | C | OR: 1.07 | 2E-15 | PubMed |
| Hypothyroidism NOS (PheCode 244.4) | C | β: 0.052 | 9E-13 | PubMed |
| Autoimmune thyroid disease | C | OR: 1.08 | 7E-12 | PubMed |
| Hypothyroidism (PheCode 244) | C | β: 0.05 | 1E-11 | PubMed |
| Lymphocytic thyroiditis | T | β: 0.086 | 6E-10 | PubMed |
| Hypothyroidism | T | β: 0.065 | 2E-9 | PubMed |
| Thyroid peroxidase antibody levels in pregnancy | T | OR: 0.12 | 5E-9 | PubMed |
| Thyroid peroxidase antibody positivity in pregnancy | T | OR: 0.84 | 8E-9 | PubMed |
| Ondansetron-induced QT prolongation | — | OR: 0.47 | 2E-7 | PubMed |