RS35677470 Unknown gene
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What This Variant Does
"rs35677470, also known as R206C, is a missense SNP in the deoxyribonuclease I-like 3 [DNASEIL3] gene..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| FCN2 protein levels | A | OR: 0.11 | 3E-35 | PubMed |
| LGMN protein levels | A | OR: 0.11 | 2E-32 | PubMed |
| Systemic sclerosis | A | OR: 2.03 | 4E-31 | PubMed |
| Serum levels of protein HIST2H2BE | A | OR: 0.39 | 1E-29 | PubMed |
| Histone H2B type 2-E levels | A | OR: 0.25 | 2E-26 | PubMed |
| Histone H2B type 3-B levels | A | OR: 0.24 | 8E-25 | PubMed |
| Limited cutaneous systemic scleroderma | A | OR: 1.62 | 1E-20 | PubMed |
| Histone H2A type 3 levels | A | OR: 0.2 | 7E-18 | PubMed |
| Serum levels of protein H2AFZ | A | OR: 0.3 | 5E-17 | PubMed |
| Serum levels of protein LST1 | A | OR: 0.28 | 8E-17 | PubMed |
| Systemic sclerosis | A | OR: 1.6 | 1E-12 | PubMed |
| C1QTNF5 protein levels | A | β: 0.071 | 1E-12 | PubMed |
| Autoimmune traits (pleiotropy) | A | — | 1E-11 | PubMed |
| Hypothyroidism | A | β: 0.047 | 1E-11 | PubMed |
| Hypothyroidism | A | β: 0.046 | 1E-11 | PubMed |
| Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) | A | OR: 1.22 | 5E-9 | PubMed |
| Autoimmune thyroid disease | A | OR: 1.1 | 9E-9 | PubMed |
| Rheumatoid arthritis | A | OR: 1.2 | 2E-8 | PubMed |
| Rheumatoid arthritis | A | OR: 1.1 | 2E-8 | PubMed |
| Rheumatoid arthritis | A | OR: 1.19 | 2E-7 | PubMed |