RS34872471 Unknown gene
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What This Variant Does
"T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Type 2 diabetes | C | OR: 0.29 | 3E-528 | PubMed |
| Type 2 diabetes (PheCode 250.2) | T | OR: 0.23 | 1E-323 | PubMed |
| Glucose (fasting status unknown, mean, inv-norm transformed) | T | OR: 0.13 | 1E-323 | PubMed |
| Hemoglobin A1c (HbA1c, mean, inv-norm transformed) | T | OR: 0.15 | 1E-323 | PubMed |
| Diabetes mellitus (PheCode 250) | T | OR: 0.23 | 1E-323 | PubMed |
| Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) | T | OR: 0.14 | 1E-323 | PubMed |
| Takes medication for Diabetes/sugar? | T | OR: 0.26 | 1E-323 | PubMed |
| Diabetes / "Sugar" | T | OR: 0.26 | 1E-323 | PubMed |
| Hemoglobin A1c (HbA1c, maximum, inv-norm transformed) | T | OR: 0.15 | 1E-323 | PubMed |
| Glucose (fasting status unknown, maximum, inv-norm transformed) | T | OR: 0.12 | 1E-323 | PubMed |
| Diabetic retinopathy (PheCode 250.7) | T | OR: 0.3 | 3E-261 | PubMed |
| Type 2 diabetes with ophthalmic manifestations (PheCode 250.23) | T | OR: 0.3 | 2E-248 | PubMed |
| Type 2 diabetes | C | OR: 0.3 | 1E-234 | PubMed |
| Type 2 diabetes (PheCode 250.2) | — | OR: 0.3 | 2E-139 | PubMed |
| Body mass index (BMI, maximum, inv-normal transformed) | T | β: 0.074 | 3E-121 | PubMed |
| Type 2 diabetes with renal manifestations (PheCode 250.22) | T | OR: 0.22 | 5E-116 | PubMed |
| Body mass index (BMI, mean, inv-normal transformed) | T | β: 0.071 | 9E-115 | PubMed |
| Weight (maximum, inv-normal transformed) | T | β: 0.069 | 8E-109 | PubMed |
| Fasting blood glucose | T | β: 0.053 | 1E-105 | PubMed |
| Weight (mean, inv-normal transformed) | T | β: 0.067 | 3E-104 | PubMed |