RS3087456 CIITA

Health Risk Chr 16:10877044 snv intron variant

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What This Variant Does

"This SNP has been linked to increased risk of adrenal insufficiency However. there is mixed informat..."

Associated Conditions

Rheumatoid arthritis

GWAS Studies (8)

Trait	Risk Allele	OR / Beta	P-value	Study
HLA DR+ T cell%T cell	A	OR: 0.46	3E-70	PubMed
HLA DR+ T cell%lymphocyte	A	OR: 0.47	7E-69	PubMed
HLA DR+ CD8+ T cell %T cell	A	OR: 0.45	1E-62	PubMed
HLA DR+ CD8+ T cell %lymphocyte	A	OR: 0.45	9E-61	PubMed
HLA DR+ T cell Absolute Count	A	OR: 0.44	4E-55	PubMed
HLA DR+ CD8+ T cell Absolute Count	A	OR: 0.43	6E-52	PubMed
HLA DR+ CD4+ T cell %lymphocyte	A	OR: 0.31	1E-33	PubMed
HLA DR+ CD4+ T cell Absolute Count	A	OR: 0.29	1E-25	PubMed

Population Frequencies

1kG AFR

91.1%

1kG ALL

62.6%

1kG AMR

55.9%

1kG EAS

88.3%

1kG EUR

76.1%

1kG SAS

42%

Other Variants in CIITA