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What This Variant Does
"UGT1A1*28 duplication allele inserts a seventh (TA) pair to six (TA) pairs this reducing the activit..."
Associated Conditions
Gilbert syndrome
Crigler-Najjar syndrome
type II
Lucey-Driscoll syndrome
BILIRUBIN
SERUM LEVEL OF
QUANTITATIVE TRAIT LOCUS 1
Irinotecan response
Crigler-Najjar syndrome type 1
UGT1A1-related disorder
Inborn genetic diseases
Irinotecan response
UGT1A9-related disorder
UGT1A1-related disorder
Inborn genetic diseases
Other Variants in covers 10 genes, none of which curated to show dosage sensitivity