RS2943641 Unknown gene
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What This Variant Does
"identified a significant association of rs2943641 near IRS1 locus, with type 2 diabetes in the Japan..."
GWAS Studies (14)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Sex hormone-binding globulin levels adjusted for BMI | T | β: 0.014 | 1E-65 | PubMed |
| Sex hormone-binding globulin levels | T | β: 0.013 | 2E-46 | PubMed |
| High density lipoprotein cholesterol levels | T | β: 0.039 | 3E-26 | PubMed |
| Triglycerides | T | β: 0.04 | 1E-23 | PubMed |
| Adiponectin levels | C | β: 0.057 | 1E-21 | PubMed |
| Triglyceride levels in VLDL | T | β: 0.035 | 4E-17 | PubMed |
| Free cholesterol to total lipids in large HDL percentage (UKB data field 23637) | T | β: 0.033 | 1E-12 | PubMed |
| Type 2 diabetes | C | OR: 1.19 | 9E-12 | PubMed |
| Insulin levels in response to oral glucose tolerance test (fasting) | T | β: 0.048 | 2E-7 | PubMed |
| Triacylglycerol (50:1) levels | T | OR: 0.15 | 7E-7 | PubMed |
| Phosphatidylethanolamine (16:0_20:4) levels | T | OR: 0.14 | 3E-6 | PubMed |
| Triacylglycerol (48:1) levels | T | OR: 0.14 | 3E-6 | PubMed |
| Triacylglycerol (50:2) levels | T | OR: 0.13 | 7E-6 | PubMed |
| Triacylglycerol (51:2) levels | T | OR: 0.13 | 1E-5 | PubMed |