RS2887399 Unknown gene
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What This Variant Does
"http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3545.html Mosaic loss of chromosome Y"
GWAS Studies (15)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Clonal hematopoiesis (mutational barcode method) | T | OR: 0.76 | 3E-63 | PubMed |
| Myeloproliferative neoplasms (MTAG) | — | β: 0.016 | 5E-20 | PubMed |
| Telomere length (principal component 1) | G | β: 0.023 | 6E-20 | PubMed |
| Clonal hematopoiesis (DNMT3A mutation) | T | OR: 1.14 | 4E-19 | PubMed |
| Basophil (fraction, mean, inv-norm transformed) | G | β: 0.042 | 4E-19 | PubMed |
| Platelet crit (UKB data field 30090) | T | β: 0.019 | 4E-18 | PubMed |
| Clonal hematopoiesis (DNMT3A mutation) | T | OR: 1.14 | 2E-15 | PubMed |
| Basophil (fraction, mean, inv-norm transformed) | G | β: 0.032 | 4E-15 | PubMed |
| Basophil (fraction, maximum, inv-norm transformed) | G | β: 0.034 | 3E-14 | PubMed |
| Clonal hematopoiesis (ASXL1 mutation) | T | OR: 0.74 | 3E-13 | PubMed |
| Basophil (fraction, minimum, inv-norm transformed) | G | β: 0.029 | 4E-12 | PubMed |
| Basophil (fraction, maximum, inv-norm transformed) | G | β: 0.027 | 4E-12 | PubMed |
| Clonal hematopoiesis (ASXL1 mutation) | T | OR: 0.76 | 5E-11 | PubMed |
| Mosaic loss of chromosome Y | G | OR: 1.57 | 6E-11 | PubMed |
| Leukocyte telomere length | T | β: 0.017 | 1E-8 | PubMed |