RS28451064 Unknown gene

Other Chr 21:34221526
Upload your DNA to see your genotype for this variant.
What This Variant Does
"Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22."
GWAS Studies (20)
Trait Risk Allele OR / Beta P-value Study
Coronary atherosclerosis (PheCode 411.4) G OR: 0.11 2E-51 PubMed
Coronary artery disease A OR: 1.12 2E-46 PubMed
Ischemic heart disease (PheCode 411) G β: 0.094 1E-42 PubMed
Coronary artery disease A OR: 0.11 3E-33 PubMed
Coronary artery disease A OR: 0.12 7E-33 PubMed
Coronary artery disease A OR: 0.12 7E-33 PubMed
Coronary atherosclerosis (PheCode 411.4) G OR: 0.11 3E-29 PubMed
Coronary artery disease or fibrinogen levels (pleiotropy) 3E-27 PubMed
Other chronic ischemic heart disease, unspecified (PheCode 411.8) G OR: 0.12 3E-27 PubMed
Coronary artery disease or von Willebrand factor levels (pleiotropy) 7E-27 PubMed
Coronary artery disease or factor VIII levels (pleiotropy) 8E-27 PubMed
Coronary artery disease or factor XI levels (pleiotropy) 9E-27 PubMed
Coronary artery disease or factor VII levels (pleiotropy) 9E-27 PubMed
Ischemic heart disease (PheCode 411) G β: 0.092 2E-23 PubMed
Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) A OR: 1.14 3E-23 PubMed
Spontaneous coronary artery dissection G OR: 2.04 1E-22 PubMed
Myocardial infarction A OR: 1.12 3E-22 PubMed
Heart failure (MTAG) A OR: 9.13 7E-20 PubMed
Myocardial infarction OR: 0.9 1E-19 PubMed
Myocardial infarction A OR: 0.15 3E-19 PubMed
Ask Dr. Hemsworth about this variant