RS28377268 Unknown gene
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What This Variant Does
"Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures."
GWAS Studies (8)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Impedance of whole body (UKB data field 23106) | T | β: 0.016 | 5E-12 | PubMed |
| Bone mineral density (spine) | T | β: 0.088 | 1E-11 | PubMed |
| Nonsyndromic orofacial clefts | — | OR: 0.85 | 8E-11 | PubMed |
| FVC x serum 25-hydroxyvitamin D interaction in never smokers (2df test) | G | — | 6E-10 | PubMed |
| Neuroticism | T | β: 0.011 | 2E-9 | PubMed |
| Lifetime major depressive disorder (AutoComplete Impute and observed) | — | β: 0.023 | 6E-9 | PubMed |
| Major depressive disorder (broad) | T | β: 0.026 | 2E-8 | PubMed |
| Bone mineral density (hip) | T | β: 0.06 | 2E-6 | PubMed |