RS28362263 Unknown gene
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What This Variant Does
"rs28362263, also known as A443T, is a SNP in the PCSK9 gene. It has been reported in several studies...
GWAS Studies (12)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Total cholesterol levels (MTAG) | A | OR: 0.13 | 1E-88 | PubMed |
| Low density lipoprotein cholesterol levels | — | OR: 9.79 | 4E-26 | PubMed |
| Low density lipoprotein cholesterol levels | — | β: 0.025 | 5E-26 | PubMed |
| Low density lipoprotein cholesterol levels | G | OR: 0.28 | 5E-24 | PubMed |
| Total cholesterol levels | — | OR: 9.62 | 9E-22 | PubMed |
| Total cholesterol levels | — | OR: 0.22 | 9E-22 | PubMed |
| Total cholesterol levels | G | OR: 0.12 | 6E-19 | PubMed |
| High-density lipoprotein levels (MTAG) | A | β: 0.027 | 3E-11 | PubMed |
| Triglyceride levels (MTAG) | A | β: 0.029 | 3E-10 | PubMed |
| Total cholesterol levels | A | OR: 0.28 | 3E-9 | PubMed |
| Low density lipoprotein cholesterol levels | G | OR: 0.28 | 5E-9 | PubMed |
| Total cholesterol levels | G | OR: 0.23 | 4E-7 | PubMed |