RS261332 Unknown gene
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What This Variant Does
"rs261332 increases susceptibility to Elevated HDL-Cholesterol for carriers of the A allele A allele ..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Low-density lipoprotein levels (MTAG) | A | β: 0.064 | 2E-310 | PubMed |
| Cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23581) | A | β: 0.095 | 1E-58 | PubMed |
| Age-related disease endophenotypes | — | — | 4E-42 | PubMed |
| Age-related diseases, mortality and associated endophenotypes | — | — | 2E-35 | PubMed |
| High density lipoprotein cholesterol levels | A | OR: 1.58 | 3E-25 | PubMed |
| Total lipids in small HDL | G | β: 0.02 | 2E-22 | PubMed |
| Postprandial triglycerides levels in IDL | G | OR: 0.26 | 2E-22 | PubMed |
| High density lipoprotein cholesterol levels | T | OR: 2.59 | 9E-21 | PubMed |
| Cholesterol levels in medium VLDL | A | β: 0.042 | 1E-16 | PubMed |
| Cholesteryl ester levels in medium VLDL | A | β: 0.041 | 2E-16 | PubMed |
| Triglyceride levels (MTAG) | A | β: 0.025 | 4E-16 | PubMed |
| Hematocrit | A | β: 0.014 | 1E-15 | PubMed |
| Fasting triglycerides levels in small LDL | G | OR: 0.19 | 1E-13 | PubMed |
| Free cholesterol levels in large LDL | A | β: 0.037 | 2E-13 | PubMed |
| Phosphatidylethanolamine(38:5)_[M-H]1- levels | G | β: 0.08 | 7E-13 | PubMed |
| Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels | G | β: 0.057 | 7E-13 | PubMed |
| Phosphatidylethanolamine(40:7)_[M-H]1- levels | T | β: 0.085 | 7E-13 | PubMed |
| Phosphatidylcholine(37:6)_[M+H]1+/Phosphatidylethanolamine(40:6)_[M+H]1+/Phosphatidate(42:7)_[M+NH4]1+ levels | G | OR: 0.19 | 7E-13 | PubMed |
| Phosphatidylcholine(33:3)_[M+H]1+/Phosphatidylethanolamine(36:3)_[M+H]1+/Phosphatidate(38:4)_[M+NH4]1+ levels | C | OR: 0.19 | 7E-13 | PubMed |
| Phosphatidylcholine(33:2)_[M+H]1+/Phosphatidylethanolamine(36:2)_[M+H]1+/Phosphatidate(38:3)_[M+NH4]1+ levels | A | OR: 0.19 | 7E-13 | PubMed |