RS2586886 Unknown gene
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What This Variant Does
"KCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension."
GWAS Studies (15)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Mean arterial pressure (BMI adjusted) | C | OR: 0.75 | 1E-25 | PubMed |
| Systolic blood pressure | T | β: 0.041 | 5E-24 | PubMed |
| Mean arterial pressure | T | β: 0.041 | 2E-22 | PubMed |
| Cryptic phenotype that captures autosomal dominant polycystic kidney disease severity | C | β: 0.01 | 4E-18 | PubMed |
| Diastolic blood pressure | T | β: 0.034 | 5E-16 | PubMed |
| Pulse pressure x alcohol consumption interaction (2df test) | T | — | 3E-14 | PubMed |
| Diastolic blood pressure | T | OR: 0.25 | 2E-12 | PubMed |
| Systolic blood pressure | T | OR: 0.4 | 6E-12 | PubMed |
| Pulse pressure | T | β: 0.028 | 1E-11 | PubMed |
| Systolic blood pressure | — | — | 1E-10 | PubMed |
| Hypertension | — | β: 0.037 | 4E-9 | PubMed |
| Diastolic blood pressure | G | OR: 0.72 | 5E-9 | PubMed |
| Diastolic blood pressure | — | OR: 0.55 | 8E-8 | PubMed |
| Treatment effectiveness of calcium channel blocker in hypertension | T | OR: 0.9 | 4E-7 | PubMed |
| Systolic blood pressure | — | OR: 0.73 | 4E-6 | PubMed |