RS25487 XRCC1

Drug Response Chr 19:43551573 snv missense variant

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What This Variant Does

"rs25487 is a SNP also known as Gln399Arg, located in the DNA repair gene XRCC1. The (A) allele encod...

Associated Conditions

Platinum compounds response - Efficacy

Spinocerebellar ataxia

autosomal recessive 26

Platinum compounds response - Efficacy

Spinocerebellar ataxia

autosomal recessive 26

Population Frequencies

gnomAD ALL

34.8%

1kG AFR

89%

1kG ALL

74%

1kG AMR

68.7%

1kG EAS

76.5%

1kG EUR

63.4%

1kG SAS

34.4%

Other Variants in XRCC1