RS2395029 HCP5;HLA-B
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What This Variant Does
"rs2395029 is a SNP in the major histocompatibility complex (MHC) region, and several studies have sh..."
Associated Conditions
Abacavir hypersensitivity
Autism spectrum disorder
Abacavir hypersensitivity
Autism spectrum disorder
Medication Interactions
Abacavir toxicity
strong
HLA-B*5701 proxy — hypersensitivity risk
GWAS Studies (7)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| LCN2/PGLYRP1 protein level ratio | — | OR: 0.4 | 6E-117 | PubMed |
| Drug-induced liver injury (flucloxacillin) | — | OR: 35.48 | 6E-97 | PubMed |
| HIV-1 control | G | OR: 5.8 | 5E-35 | PubMed |
| Drug-induced liver injury (flucloxacillin) | — | OR: 45 | 9E-33 | PubMed |
| Psoriasis | C | OR: 4.1 | 2E-26 | PubMed |
| HIV-1 control | G | OR: 5.3 | 1E-25 | PubMed |
| AIDS progression | G | OR: 3.47 | 3E-19 | PubMed |