RS2292334 Unknown gene
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What This Variant Does
"Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver"
GWAS Studies (9)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Type 2 diabetes mellitus adjusted for BMI or coronary artery disease (pleiotropy) | — | — | 3E-51 | PubMed |
| monocyte (fraction, maximum, inv-norm transformed) | G | β: 0.025 | 1E-14 | PubMed |
| mean corpuscular hemoglobin (MCH, mean, inv-norm transformed) | G | β: 0.021 | 6E-14 | PubMed |
| Monocyte count | A | β: 0.013 | 3E-12 | PubMed |
| mean corpuscular hemoglobin (MCH, minimum, inv-norm transformed) | G | β: 0.02 | 4E-12 | PubMed |
| Monocyte percentage of white cells | A | β: 0.015 | 2E-11 | PubMed |
| Hip circumference adjusted for BMI | A | β: 0.018 | 2E-10 | PubMed |
| Monocyte count | A | β: 0.013 | 3E-9 | PubMed |
| Skeletal muscle LPA levels | A | — | 2E-6 | PubMed |