RS2235544 DIO1
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What This Variant Does
"(Published 2008) Researchers noted that reduced fT3/fT4 ratios may be significant, since various bod..."
Associated Conditions
Levothyroxine response
Levothyroxine response
GWAS Studies (9)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Thyroxine levels | A | β: 0.096 | 6E-197 | PubMed |
| Free thyroxine concentration | A | OR: 0.15 | 5E-34 | PubMed |
| Thyroid hormone levels | A | OR: 0.13 | 3E-18 | PubMed |
| Height | A | β: 0.006 | 1E-13 | PubMed |
| Free T4 levels | A | β: 0.026 | 4E-13 | PubMed |
| Thyroxine levels | C | OR: 0.1 | 5E-12 | PubMed |
| Hypothyroidism | A | β: 0.024 | 5E-11 | PubMed |
| Red blood cell count | A | β: 0.006 | 6E-9 | PubMed |
| Multiple myeloma (hyperdiploidy) | A | OR: 1.3 | 6E-7 | PubMed |
Population Frequencies
gnomAD ALL
0%
1kG AFR
16.3%
1kG ALL
46%
1kG AMR
35.9%
1kG EAS
53.9%
1kG EUR
47.5%
1kG SAS
66.7%
Other Variants in DIO1