RS2187668 Unknown gene
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What This Variant Does
"In at least UK populations, and perhaps others, SNP rs2187668 is a tag SNP for the HLA-DRB1*0301 all..."
GWAS Studies (16)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Idiopathic membranous nephropathy | A | OR: 4.32 | 8E-93 | PubMed |
| Autoimmune hepatitis type-1 | — | OR: 2.9 | 2E-78 | PubMed |
| PLA2G15 protein levels | T | OR: 0.12 | 4E-77 | PubMed |
| Celiac disease | A | OR: 6.23 | 1E-50 | PubMed |
| Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) | A | OR: 3.4 | 5E-36 | PubMed |
| Immunoglobulin A | A | OR: 2.53 | 2E-33 | PubMed |
| Systemic lupus erythematosus | A | OR: 2.23 | 6E-28 | PubMed |
| Systemic lupus erythematosus | A | — | 3E-21 | PubMed |
| Celiac disease | A | OR: 7.04 | 1E-19 | PubMed |
| Collagenous colitis | — | OR: 2.06 | 2E-11 | PubMed |
| Diastolic blood pressure | T | OR: 0.37 | 4E-11 | PubMed |
| Cutaneous lupus erythematosus | T | OR: 2.93 | 4E-10 | PubMed |
| Systemic lupus erythematosus | — | — | 1E-9 | PubMed |
| Inflammatory bowel disease | — | OR: 1.96 | 2E-7 | PubMed |
| Ulcerative colitis | — | OR: 2.21 | 4E-6 | PubMed |
| Diastolic blood pressure | T | β: 0.026 | 8E-6 | PubMed |