RS2074356 Unknown gene
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What This Variant Does
"rs2074356 is a SNP in an uncharacterized locus on ch 12 known as the chromosome 12 open reading fram..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Gamma glutamyl transpeptidase | T | β: 0.016 | 3E-126 | PubMed |
| Alcohol consumption | T | OR: 1.06 | 9E-59 | PubMed |
| Alcohol consumption (drinkers vs non-drinkers) | A | OR: 2.41 | 6E-48 | PubMed |
| HDL cholesterol | T | β: 0.035 | 7E-37 | PubMed |
| Esophageal cancer | T | OR: 1.56 | 2E-31 | PubMed |
| Body mass index | A | β: 0.066 | 3E-31 | PubMed |
| Metabolic syndrome | — | — | 2E-23 | PubMed |
| Weight | A | β: 0.038 | 2E-21 | PubMed |
| Blood urea nitrogen levels | A | β: 0.019 | 5E-18 | PubMed |
| Estimated glomerular filtration rate | A | OR: 0.81 | 2E-17 | PubMed |
| Aspartate aminotransferase to alanine aminotransferase ratio x alcohol consumption interaction | — | β: 0.005 | 9E-17 | PubMed |
| Coffee consumption | A | OR: 0.19 | 2E-16 | PubMed |
| Glycemic traits | T | OR: 0.17 | 6E-14 | PubMed |
| Hypertension | A | OR: 0.78 | 3E-13 | PubMed |
| Biomedical quantitative traits | T | β: 0.01 | 8E-12 | PubMed |
| Type 2 diabetes | A | OR: 0.8 | 1E-11 | PubMed |
| Type 2 diabetes | A | OR: 0.7 | 6E-11 | PubMed |
| Mean corpuscular volume | A | β: 0.004 | 2E-10 | PubMed |
| High density lipoprotein cholesterol levels | — | — | 2E-9 | PubMed |
| Renal function-related traits (BUN) | A | β: 0.006 | 2E-9 | PubMed |