RS2066827 CDKN1B

Health Risk Chr 12:12718165

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What This Variant Does

"CLNSIG=3

Associated Conditions

Multiple endocrine neoplasia type 4

Hereditary cancer-predisposing syndrome

CDKN1B-related disorder

Multiple endocrine neoplasia type 4

Hereditary cancer-predisposing syndrome

Multiple endocrine neoplasia type 4

Hereditary cancer-predisposing syndrome

CDKN1B-related disorder

Multiple endocrine neoplasia type 4

Hereditary cancer-predisposing syndrome

GWAS Studies (20)

Trait	Risk Allele	OR / Beta	P-value	Study
Height	G	β: 0.021	1E-169	PubMed
Standing height (UKB data field 50)	G	β: 0.013	3E-27	PubMed
height (mean, inv-normal transformed)	T	β: 0.04	2E-25	PubMed
Height	—	β: 0.021	9E-25	PubMed
Height (maximum, inv-normal transformed)	T	β: 0.038	3E-24	PubMed
Weight (mean, inv-normal transformed)	T	β: 0.032	5E-23	PubMed
Height (baseline)	T	β: 0.015	8E-23	PubMed
height (minimum, inv-normal transformed)	T	β: 0.036	1E-22	PubMed
Weight (maximum, inv-normal transformed)	T	β: 0.03	4E-20	PubMed
Weight (minimum, inv-normal transformed)	T	β: 0.028	2E-19	PubMed
What is your height? (cm, inv-normal transformed)	T	β: 0.039	2E-18	PubMed
height (mean, inv-normal transformed)	T	β: 0.039	1E-17	PubMed
Height (maximum, inv-normal transformed)	T	β: 0.039	3E-17	PubMed
Appendicular lean mass	T	β: 0.018	2E-16	PubMed
Type 2 diabetes	G	—	7E-16	PubMed
height (minimum, inv-normal transformed)	T	β: 0.034	1E-14	PubMed
Physical function (baseline)	T	β: 0.009	2E-13	PubMed
Weight (minimum, inv-normal transformed)	T	β: 0.025	4E-13	PubMed
Whole body water mass (UKB data field 23102)	G	β: 0.009	2E-12	PubMed
Basal metabolic rate (UKB data field 23105)	G	β: 0.009	9E-12	PubMed

Other Variants in CDKN1B