RS20541 IL13
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What This Variant Does
"rs20541 is a C/T polymorphism on the interleukin 13 gene IL13 associated with IgE levels. rs20541 in...
Associated Conditions
Inherited susceptibility to asthma
Allergic rhinitis
susceptibility to
IL13-related disorder
Inherited susceptibility to asthma
Allergic rhinitis
susceptibility to
IL13-related disorder
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Atopic dermatitis | G | OR: 0.92 | 1E-129 | PubMed |
| Atopic dermatitis | A | OR: 0.11 | 2E-35 | PubMed |
| Atopic asthma | — | — | 1E-21 | PubMed |
| Atopic dermatitis | G | OR: 0.15 | 1E-18 | PubMed |
| IgE levels | A | β: 0.08 | 3E-18 | PubMed |
| Asthma | A | OR: 1.12 | 5E-16 | PubMed |
| Psoriasis | G | OR: 1.27 | 5E-15 | PubMed |
| Atopic dermatitis | — | OR: 0.91 | 7E-15 | PubMed |
| Asthma | G | OR: 0.12 | 1E-14 | PubMed |
| Eczema | A | OR: 1.17 | 2E-14 | PubMed |
| Eczema | G | OR: 0.12 | 4E-14 | PubMed |
| Hay fever and/or eczema | A | OR: 1.06 | 5E-13 | PubMed |
| Psoriasis | G | OR: 1.14 | 5E-9 | PubMed |
| Lymphocyte count | G | β: 0.017 | 7E-9 | PubMed |
| Childhood asthma with severe exacerbations | A | OR: 1.21 | 1E-8 | PubMed |
| Hodgkin's lymphoma | — | OR: 1.47 | 1E-8 | PubMed |
| Cutaneous psoriasis | G | OR: 1.24 | 3E-8 | PubMed |
| Allergic sensitization | A | OR: 1.14 | 5E-7 | PubMed |
| Self-reported allergy | A | β: 0.072 | 1E-6 | PubMed |
| Psoriasis | A | OR: 1.19 | 5E-6 | PubMed |
Other Variants in IL13