RS200383755 GATA5
Upload your DNA to see your genotype for this variant.
What This Variant Does
"95 
Associated Conditions
GATA5-related disorder
Congenital heart defects
multiple types
5
GATA5-related disorder
Congenital heart defects
multiple types
5
GWAS Studies (19)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Lung function (FVC) | — | OR: 0.11 | 5E-18 | PubMed |
| Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256) | C | OR: 0.1 | 9E-16 | PubMed |
| Diastolic blood pressure | — | β: 0.095 | 4E-15 | PubMed |
| Chronic obstructive pulmonary disease liability (machine learning-based score) | G | OR: 0.11 | 6E-14 | PubMed |
| Diastolic blood pressure | C | β: 0.097 | 1E-13 | PubMed |
| Systolic blood pressure | — | β: 0.09 | 1E-13 | PubMed |
| Diastolic blood pressure | — | β: 0.091 | 2E-13 | PubMed |
| Systolic blood pressure | — | β: 0.083 | 4E-13 | PubMed |
| Lung function (FEV1) | C | OR: 7.14 | 1E-12 | PubMed |
| Forced expiratory volume in 1 second (FEV1) | — | — | 1E-12 | PubMed |
| Estimated glomerular filtration rate (creatinine, cystatin c) | C | β: 0.1 | 2E-12 | PubMed |
| Systolic blood pressure | C | β: 0.09 | 3E-12 | PubMed |
| Cystatin C levels | — | β: 0.076 | 3E-12 | PubMed |
| Benign prostatic hyperplasia and lower urinary tract symptoms | G | OR: 1.61 | 7E-12 | PubMed |
| Creatinine levels | — | β: 0.075 | 9E-11 | PubMed |
| Benign prostatic hyperplasia and lower urinary tract symptoms (prostate cancer excluded) | G | OR: 1.56 | 1E-9 | PubMed |
| Estimated glomerular filtration rate (cystatin c) | C | β: 0.086 | 2E-9 | PubMed |
| Forced vital capacity (FVC) | — | — | 1E-8 | PubMed |
| Estimated glomerular filtration rate (creatinine) | C | β: 0.08 | 2E-8 | PubMed |
Other Variants in GATA5