RS1893592 Unknown gene
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What This Variant Does
"One of 42 more SNPs associated with rheumatoid arthritis based on a meta-analysis of 30,000 patients..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Graves' disease | C | OR: 0.12 | 1E-14 | PubMed |
| Rheumatoid arthritis | A | OR: 1.1 | 2E-13 | PubMed |
| Primary sclerosing cholangitis | A | OR: 1.22 | 2E-12 | PubMed |
| Lymphocyte count | C | β: 0.015 | 2E-12 | PubMed |
| Autoimmune traits (pleiotropy) | C | — | 5E-12 | PubMed |
| Rheumatoid arthritis | A | OR: 1.11 | 7E-12 | PubMed |
| Lymphocyte count (UKB data field 30120) | C | β: 0.014 | 1E-11 | PubMed |
| Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) | C | OR: 0.91 | 2E-11 | PubMed |
| Rheumatoid arthritis (ACPA-positive) | A | OR: 1.12 | 8E-11 | PubMed |
| Celiac disease and Rheumatoid arthritis | — | OR: 0.91 | 8E-11 | PubMed |
| Celiac disease | — | OR: 1.14 | 9E-11 | PubMed |
| Rheumatoid arthritis | C | OR: 0.93 | 1E-10 | PubMed |
| Lymphocyte count | C | β: 0.015 | 2E-10 | PubMed |
| Type 1 diabetes | — | OR: 1.16 | 2E-9 | PubMed |
| Celiac disease | — | OR: 1.14 | 3E-9 | PubMed |
| Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) | — | — | 6E-9 | PubMed |
| Inflammatory bowel disease | C | OR: 0.91 | 8E-9 | PubMed |
| Rheumatoid arthritis | A | OR: 0.1 | 1E-8 | PubMed |
| Sarcoidosis | A | OR: 1.11 | 1E-8 | PubMed |
| Neutrophils and lymphocytes in blood (confirmatory factor analysis Factor 35) | — | — | 2E-8 | PubMed |