RS1801253 ADRB1
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What This Variant Does
"Also known as Arg389, variation at this SNP, located in the ADRB1 gene, may encode either the amino ...
Associated Conditions
Pulmonary disease
chronic obstructive
susceptibility to
ADRB1-related disorder
Pulmonary disease
chronic obstructive
susceptibility to
ADRB1-related disorder
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Triglycerides to Total Lipids in Medium HDL percentage | C | β: 0.03 | 4E-32 | PubMed |
| Cholesterol to Total Lipids in Medium HDL percentage | C | β: 0.02 | 1E-30 | PubMed |
| Triglycerides to Total Lipids in Small HDL percentage | C | β: 0.02 | 7E-30 | PubMed |
| Cholesteryl Esters to Total Lipids in Medium HDL percentage | C | β: 0.02 | 5E-29 | PubMed |
| Hypertension | C | β: 0.059 | 6E-27 | PubMed |
| Triglycerides in small HDL | C | β: 0.02 | 1E-24 | PubMed |
| Systolic blood pressure | — | β: 0.022 | 3E-24 | PubMed |
| Cardiovascular disease | — | — | 6E-24 | PubMed |
| Phospholipids to Total Lipids in Medium HDL percentage | C | β: 0.02 | 7E-23 | PubMed |
| Systolic blood pressure (cigarette smoking interaction) | — | — | 1E-22 | PubMed |
| Diastolic blood pressure (cigarette smoking interaction) | — | — | 3E-22 | PubMed |
| diastolic blood pressure (DBP, mean, inv-normal transformed) | G | β: 0.028 | 3E-22 | PubMed |
| Triglyceride to phosphoglyceride ratio | C | β: 0.02 | 3E-21 | PubMed |
| Triglycerides in very small VLDL | C | β: 0.02 | 4E-20 | PubMed |
| Triglycerides in HDL | C | β: 0.02 | 2E-19 | PubMed |
| Triglycerides in medium HDL | C | β: 0.02 | 6E-19 | PubMed |
| Concentration of very large VLDL particles | C | β: 0.02 | 2E-18 | PubMed |
| Phospholipids in large VLDL | C | β: 0.02 | 4E-18 | PubMed |
| Triglycerides in IDL | C | β: 0.02 | 6E-18 | PubMed |
| Total triglycerides levels | C | β: 0.02 | 2E-17 | PubMed |
Other Variants in ADRB1