RS1800961 Unknown gene
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What This Variant Does
"per the 23andMe blog, the minor allele of this SNP (T) was associated with decreased HDL cholesterol...
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| High density lipoprotein cholesterol levels | — | — | 1E-268 | PubMed |
| high density lipoprotein cholesterol (HDLC, mean, inv-norm transformed) | C | OR: 0.28 | 3E-236 | PubMed |
| high density lipoprotein cholesterol (HDLC, minimm, inv-norm transformed) | C | OR: 0.26 | 1E-211 | PubMed |
| high density lipoprotein cholesterol (HDLC, maximum, inv-norm transformed) | C | OR: 0.26 | 1E-208 | PubMed |
| High-density lipoprotein levels | T | OR: 0.19 | 9E-190 | PubMed |
| High density lipoprotein cholesterol levels | T | OR: 0.13 | 3E-157 | PubMed |
| Apolipoprotein A1 levels | C | OR: 0.15 | 2E-152 | PubMed |
| Apolipoprotein A levels (UKB data field 30630) | T | OR: 0.13 | 7E-142 | PubMed |
| HDL cholesterol levels | C | OR: 0.14 | 1E-140 | PubMed |
| Concentration of HDL particles | T | OR: 0.13 | 2E-134 | PubMed |
| Haematocrit percentage (UKB data field 30030) | T | OR: 0.12 | 2E-134 | PubMed |
| Total concentration of lipoprotein particles | T | OR: 0.13 | 2E-123 | PubMed |
| Apolipoprotein A1 levels | T | OR: 0.12 | 4E-121 | PubMed |
| high density lipoprotein cholesterol (HDLC, mean, inv-norm transformed) | C | OR: 0.23 | 4E-119 | PubMed |
| Cholesterol in Medium HDL | T | OR: 0.12 | 4E-117 | PubMed |
| Free cholesterol in medium HDL | T | OR: 0.12 | 1E-116 | PubMed |
| Cholesteryl Esters in Medium HDL | T | OR: 0.12 | 5E-115 | PubMed |
| high density lipoprotein cholesterol (HDLC, maximum, inv-norm transformed) | C | OR: 0.22 | 3E-113 | PubMed |
| Total cholesterol levels | — | — | 2E-111 | PubMed |
| Concentration of medium HDL particles | T | OR: 0.12 | 1E-110 | PubMed |