RS174570 Unknown gene
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What This Variant Does
"per the 23andMe blog, the minor allele of this SNP (T) was associated with decreased cholesterol and..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Height | T | β: 0.023 | 1E-146 | PubMed |
| Lysophosphatidylethanolamine_22:4_[M-H]1- levels | T | OR: 0.31 | 6E-110 | PubMed |
| Lysophosphatidylcholine_20:4_[M+H]1+ levels | T | OR: 0.38 | 1E-106 | PubMed |
| Stearidonic acid levels (275.2014_0.36) | — | OR: 0.3 | 6E-81 | PubMed |
| Stearidonic acid levels (275.2014_0.36) x waist circumference interaction (2df) | — | — | 1E-78 | PubMed |
| High density lipoprotein cholesterol levels | T | β: 0.061 | 3E-59 | PubMed |
| Cholesteryl ester_20:5_[M+NH4]1+ levels | T | OR: 0.27 | 2E-54 | PubMed |
| Phosphatidylethanolamine_38:4_[M-H]1- levels | T | OR: 0.19 | 8E-52 | PubMed |
| Fatty acid(20:4)_[M-H]1- levels | T | OR: 0.17 | 1E-50 | PubMed |
| Total cholesterol levels | T | β: 0.053 | 7E-50 | PubMed |
| Cholesteryl ester_20:3_[M+NH4]1+ levels | T | OR: 0.22 | 2E-49 | PubMed |
| Phosphatidylcholine_37:4_[M+H]1+/Phosphatidylethanolamine_40:4_[M+H]1+/Phosphatidate_42:5_[M+NH4]1+ levels | T | OR: 0.33 | 1E-48 | PubMed |
| Phosphatidylcholine_38:5_[M+H]1+/Phosphatidylethanolamine_41:5_[M+H]1+/Phosphatidate_43:6_[M+NH4]1+ levels | T | OR: 0.32 | 1E-47 | PubMed |
| Apolipoprotein B levels | T | β: 0.051 | 4E-46 | PubMed |
| Phosphatidylcholine_34:2_[M+OAc]1-/Phosphatidylserine_38:1_[M-H]1- levels | T | OR: 0.19 | 8E-42 | PubMed |
| Triglyceride levels | T | β: 0.049 | 2E-41 | PubMed |
| Phosphatidylcholine_34:2_[M+H]1+/Phosphatidylethanolamine_37:2_[M+H]1+/Phosphatidate_39:3_[M+NH4]1+ levels | T | OR: 0.23 | 2E-41 | PubMed |
| 1-(1-enyl-stearoyl)-2-linoleoyl-GPE (p-18:0/18:2) levels | T | OR: 0.2 | 1E-39 | PubMed |
| Serum alkaline phosphatase levels | T | β: 0.046 | 5E-38 | PubMed |
| Phosphatidylethanolamine_34:2_[M-H]1- levels | T | OR: 0.22 | 4E-37 | PubMed |