Genetic variant

rs174556

rs174556 is a single-letter difference in human DNA, on chromosome 11. Carrying it does not, on its own, mean you have or will develop any condition.

Register free Do I have this variant?

What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs174556 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs174556, if your test read this position.

Register free Upload DNA Log in

Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

Upload blood results

What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
Register free Upload DNA Upload blood results Ask Dr. Hemsworth

This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs174556
Position
chr11:61813163

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
Phosphatidylcholine (18:1_20:3) levels T OR 0.51 1E-108 PubMed
Alkylphosphatidylcholine (O-16:0/20:3) levels T OR 0.48 2E-97 PubMed
Phosphatidylcholine (16:0_20:3) (a) levels T OR 0.42 2E-73 PubMed
Alkylphosphatidylcholine (O-16:0/20:3) levels T OR 0.41 1E-68 PubMed
Phosphatidylcholine (18:1_20:3) levels T OR 0.4 4E-66 PubMed
Phosphatidylethanolamine (18:0_18:2) levels T OR 0.37 2E-61 PubMed
Cholesteryl ester (20:2) levels T OR 0.38 3E-60 PubMed
red cell diameter width (RDW, minimum, inv-norm transformed) C β 0.053 2E-56 PubMed
Phosphatidylcholine (16:0_20:3) (a) levels T OR 0.31 2E-39 PubMed
mean corpuscular hemoglobin concentration (MCHC, mean, inv-norm transformed) C β 0.036 2E-37 PubMed
Phosphatidylethanolamine (O-18:2_20:4) levels T OR 0.18 4E-26 PubMed
low density lipoprotein cholesterol (LDLC, mean, inv-norm transformed) C β 0.027 1E-23 PubMed
Eicosapentaenoate EPA; 20:5n3 levels T β 0.036 2E-22 PubMed
Serum metabolite levels C OR 0.24 6E-22 PubMed
Cholesteryl ester (20:2) levels T OR 0.23 6E-22 PubMed
low density lipoprotein cholesterol (LDLC, maximum, inv-norm transformed) C β 0.028 7E-22 PubMed
low density lipoprotein cholesterol (LDLC, mean, inv-norm transformed) C β 0.028 5E-21 PubMed
1-stearyl-GPC (O-18:0) levels T OR 0.1 2E-20 PubMed
1-stearoyl-2-arachidonoyl-gpc (18:0/20:4) levels (elderly offspring) — OR 0.11 4E-20 PubMed
Phosphatidylcholine (14:0_18:2) levels T OR 0.21 8E-20 PubMed

Sources