RS174537 Unknown gene
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What This Variant Does
"rs174537 is a SNP near the FADS1 gene on chromosome 11. The FADS1 gene is one of 3 fatty acid desatu..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Phosphatidylcholine (18:0_20:4) levels | T | OR: 0.68 | 1E-386 | PubMed |
| Polyunsaturated fatty acids to total fatty acids percentage | T | — | 1E-300 | PubMed |
| Triglycerides to Total Lipids in Very Small VLDL percentage | T | OR: 0.1 | 1E-273 | PubMed |
| Cholesteryl Esters to Total Lipids in Very Small VLDL percentage | T | β: 0.1 | 2E-264 | PubMed |
| Triglycerides to Total Lipids in IDL percentage | T | β: 0.092 | 4E-229 | PubMed |
| Phosphatidylcholine (18:1_20:4) levels | T | OR: 0.51 | 5E-207 | PubMed |
| Phosphatidylcholine (16:0_20:4) levels | T | OR: 0.61 | 7E-178 | PubMed |
| Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) | T | OR: 0.53 | 4E-164 | PubMed |
| Triglycerides to Total Lipids in Very Small VLDL percentage | T | β: 0.076 | 1E-128 | PubMed |
| Triglycerides to total lipids ratio in very small VLDL | G | β: 0.098 | 5E-126 | PubMed |
| Phosphatidylcholine (18:1_20:4) levels | T | OR: 0.51 | 8E-120 | PubMed |
| Cholesteryl Esters to Total Lipids in Very Small VLDL percentage | T | β: 0.071 | 1E-114 | PubMed |
| Free cholesterol to total lipids ratio in medium VLDL | G | β: 0.092 | 3E-109 | PubMed |
| Triglycerides to Total Lipids in IDL percentage | T | β: 0.068 | 6E-107 | PubMed |
| Triglycerides to total lipids in very small VLDL percentage (UKB data field 23608) | T | β: 0.099 | 3E-97 | PubMed |
| Free cholesterol to total lipids ratio in small VLDL | G | β: 0.083 | 1E-90 | PubMed |
| Cholesterol to total lipids ratio in medium VLDL | G | β: 0.081 | 2E-87 | PubMed |
| Phospholipids in small LDL | T | β: 0.04 | 1E-86 | PubMed |
| Triglycerides | T | β: 0.062 | 2E-86 | PubMed |
| Free cholesterol to total lipids in medium VLDL percentage (UKB data field 23597) | T | β: 0.092 | 4E-82 | PubMed |