RS16891982 Unknown gene
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What This Variant Does
"This snp influences skin pigmentation. The allele p.L374F indicates light-skinned european ancestry ...
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Sunburns | — | — | 3E-320 | PubMed |
| Actinic keratosis (PheCode 702.1) | C | OR: 0.6 | 2E-311 | PubMed |
| Brown vs. black hair color | — | OR: 2.83 | 2E-308 | PubMed |
| Urea levels | — | — | 1E-263 | PubMed |
| Eye color | G | OR: 0.65 | 2E-255 | PubMed |
| Actinic keratosis (PheCode 702.1) | C | OR: 0.63 | 4E-255 | PubMed |
| Skin cancer | C | OR: 0.56 | 1E-240 | PubMed |
| Other non-epithelial cancer of skin (PheCode 172.2) | C | OR: 0.54 | 1E-181 | PubMed |
| Blond vs. brown/black hair color | — | OR: 3.29 | 3E-181 | PubMed |
| Low tan response | C | OR: 0.92 | 2E-176 | PubMed |
| Degenerative skin conditions and other dermatoses (PheCode 702) | C | OR: 0.37 | 7E-175 | PubMed |
| Skin cancer | C | OR: 0.51 | 8E-174 | PubMed |
| Skin phototype score | C | OR: 9.47 | 3E-150 | PubMed |
| Melanomas of skin, dx or hx (PheCode 172.1) | C | OR: 0.61 | 2E-141 | PubMed |
| Skin color | C | OR: 0.55 | 1E-140 | PubMed |
| Other non-epithelial cancer of skin (PheCode 172.2) | C | OR: 0.5 | 2E-140 | PubMed |
| Degenerative skin conditions and other dermatoses (PheCode 702) | C | OR: 0.32 | 3E-135 | PubMed |
| Skin cancer | C | OR: 0.54 | 6E-134 | PubMed |
| Melanomas of skin, dx or hx (PheCode 172.1) | C | OR: 0.58 | 8E-128 | PubMed |
| Skin cancer | C | OR: 0.52 | 8E-118 | PubMed |