RS168622 Unknown gene
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What This Variant Does
"SNPs affecting serum metabolomic traits may regulate gene transcription and lipid accumulation in the liver"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Ceramide (d19:1/20:0) levels | G | OR: 0.54 | 1E-136 | PubMed |
| Ceramide (d19:1/20:0) levels | G | OR: 0.52 | 3E-124 | PubMed |
| Ceramide (d20:1/24:0) levels | G | OR: 0.49 | 1E-110 | PubMed |
| Ceramide (d20:1/24:0) levels | G | OR: 0.45 | 1E-91 | PubMed |
| Triglycerides to Total Lipids in IDL percentage | G | β: 0.03 | 1E-49 | PubMed |
| Metabolite levels (sphingomyelin (d18:0/20:0, d16:0/22:0)) | G | OR: 0.27 | 5E-47 | PubMed |
| Triglycerides to Total Lipids in Very Small VLDL percentage | G | β: 0.02 | 3E-37 | PubMed |
| Cholesterol to Total Lipids in Very Small VLDL percentage | G | β: 0.02 | 3E-37 | PubMed |
| Cholesterol to Total Lipids in IDL percentage | G | β: 0.02 | 1E-36 | PubMed |
| Cholesteryl Esters to Total Lipids in Very Small VLDL percentage | G | β: 0.02 | 7E-36 | PubMed |
| Metabolite levels (myristoyl dihydrosphingomyelin (d18:0/14:0)) | G | OR: 0.23 | 1E-33 | PubMed |
| Ceramide (d18:1/22:0) levels | G | OR: 0.26 | 2E-32 | PubMed |
| Cholesterol to Total Lipids in Large LDL percentage | G | β: 0.02 | 3E-31 | PubMed |
| Ceramide (d18:1/22:0) levels | G | OR: 0.23 | 9E-26 | PubMed |
| Triglycerides to Total Lipids in Small LDL percentage | G | β: 0.02 | 1E-25 | PubMed |
| Free Cholesterol to Total Lipids in Large LDL percentage | G | β: 0.02 | 9E-25 | PubMed |
| Free Cholesterol to Total Lipids in Small VLDL percentage | G | β: 0.02 | 4E-23 | PubMed |
| Sphingomyelin (d18:1/22:2, d18:2/22:1, d16:1/24:2) levels | G | OR: 0.19 | 1E-22 | PubMed |
| Sphingomyelin(37:1)_[M+H]1+ levels | C | β: 0.052 | 1E-22 | PubMed |
| Sphingomyelin(39:1)_[M+H]1+ levels | G | OR: 0.15 | 1E-22 | PubMed |