RS1333042 CDKN2B-AS1
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What This Variant Does
"rs1333042 increases susceptibility to Coronary artery disease 1.29 times for heterozygotes (AG) and ..."
Associated Conditions
Three Vessel Coronary Disease
Three Vessel Coronary Disease
GWAS Studies (15)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Coronary artery / coronary heart disease (including heart attack, angina) | A | OR: 0.18 | 8E-129 | PubMed |
| Takes medication for coronary artery/ coronary heart disease? | A | OR: 0.17 | 9E-109 | PubMed |
| Ischemic heart disease (PheCode 411) | G | — | 2E-72 | PubMed |
| Medication use for hyperlipidemia (number of purchases) | — | β: 0.017 | 3E-41 | PubMed |
| Parental longevity (father's age at death) | A | β: 0.02 | 7E-15 | PubMed |
| Other chronic ischemic heart disease, unspecified (PheCode 411.8) | A | OR: 0.16 | 9E-14 | PubMed |
| Total lipid levels in chylomicrons and extremely large VLDL | G | β: 0.01 | 5E-12 | PubMed |
| Triglyceride levels in chylomicrons and extremely large VLDL | G | β: 0.01 | 6E-12 | PubMed |
| Concentration of chylomicrons and extremely large VLDL particles | G | β: 0.01 | 2E-10 | PubMed |
| Coronary heart disease | — | OR: 1.3 | 1E-9 | PubMed |
| Endometriosis or asthma (pleiotropy) | A | β: 0.06 | 1E-9 | PubMed |
| Asthma and cardiovascular disease | — | — | 3E-9 | PubMed |
| Parental longevity (both parents in top 10%) | A | β: 0.011 | 2E-8 | PubMed |
| Parental longevity (mother's age at death or mother's attained age) | G | — | 3E-7 | PubMed |
| Coronary artery disease | — | β: 0.07 | 6E-6 | PubMed |
Other Variants in CDKN2B-AS1