RS1317286 Unknown gene
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What This Variant Does
"Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans"
GWAS Studies (9)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Cigarettes smoked per day | G | OR: 0.11 | 3E-40 | PubMed |
| Parental longevity (father's attained age) | A | — | 2E-31 | PubMed |
| Chronic obstructive pulmonary disease in ever smokers | G | OR: 1.19 | 5E-28 | PubMed |
| Parental longevity (combined parental attained age, Martingale residuals) | A | β: 0.025 | 1E-26 | PubMed |
| Chronic obstructive pulmonary disease x ever smoker interaction (2df) | G | — | 3E-25 | PubMed |
| Post bronchodilator FEV1 | A | β: 0.07 | 3E-14 | PubMed |
| Post bronchodilator FEV1/FVC ratio | A | β: 0.014 | 3E-14 | PubMed |
| Parental longevity (mother's attained age) | A | — | 2E-7 | PubMed |
| Post bronchodilator FEV1/FVC ratio in COPD | A | β: 0.012 | 4E-7 | PubMed |